-
- In 2007, Vioxx's manufacturer Merck was judged to pay a $4.85 billion settlement to thousands of claims for heart attacks, strokes and deaths.Pharmalot: NJ Supreme Court To Hear Vioxx Preemption (October 13, 2008)
- Merck is appealing that settlement, arguing that since the FDA approved Vioxx, Merck shouldn't be liable for compensatory damagesPharmalot: NJ Supreme Court To Hear Vioxx Preemption (October 13, 2008)
- A 2005 study by the same research team found that the risk of strokes did not increase until after 18 months of using Vioxx, a finding that played a role in Merck's defense.Reuters: Long-term study confirms Vioxx heart risks (October 13, 2008)
-
-
A three-year study of users of the now-banned arthritis painkiller Vioxx supports the conclusion that it doubles the risk of heart attacks and strokes. The study reveals that the risk persists even after the user stops taking it, for up to a year.Washington Post: Vioxx's Heart Risk Lingered Long After Use Ended (October 13, 2008)
In addition, the researchers believe that long-term risks may also be associated with cox-2 pain inhibitors present in Celebrex, as well as with non-steroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen and naproxen.Washington Post: Vioxx's Heart Risk Lingered Long After Use Ended (October 13, 2008) Reuters: Long-term study confirms Vioxx heart risks (October 13, 2008)
Quotes
""There seems to be an increased risk for most if not all non-steroidal anti-inflammatory drugs. That doesn't mean these aren't good drugs. It's just there is some increased risk we need to be aware of." -- Dr. Robert BresalierReuters: Long-term study confirms Vioxx heart risks (October 13, 2008)"There was always a signal that it [the risk] was worse for Vioxx that other cox-2 inhibitors. Whether or not other drugs like Celebrex shared that isn't known. That has not been demonstrated in studies of Celebrex. But you have to be suspicious, particularly since high doses of Celebrex have heart attack and stroke risk. But there's never been a study to show that it's a long-lasting liability." -- Dr. Eric J. TopolWashington Post: Vioxx's Heart Risk Lingered Long After Use Ended (October 13, 2008)
-
-
Vioxx Risk Study Questions
-
What is High Risk Pregnancy? 2 AnswersPregnancies at high risk of fetal or maternal complications. There are many factors that contribute to complications during pregnancy and delivery. A pregnancy,... read more -
Are there any risks to over-sanitizing? 4 AnswersOversanitizing can have negative consequences. First, some antibacterials contain a substance called triclosan. Triclosan is a chlorphenol, and is registered wi... read more -
Why is there no risk of explosion when connecting a negative jumper cable to negative terminal wheras in a dead battery there is a risk? 1 AnswerThere is equal risk with either connection, it depends on which one you connect last. As the last connection is made, there will likely be some sparks which co... read more
-
