The Devil's Rejects is the sequel to the 2003 horror film, House of 1000 Corpses. Rob Zombie is the writer and producer of these horror films. Other films by Rob Zombie include Halloween 2007.

In the beginning of the movie state troopers surround the home of the "Firefly" family and after a brutal shoot-out where "Rufus" is killed they take "Mother Firefly" into custody. "Tiny" is missing but brother and sister "Otis" and "Baby" escape. They hide out in a run-down hotel where they torture and kill a family of five. Soon they meet up with their father "Captain Spaulding" and head to a seedy whorehouse run by a Captain Spaulding's adopted brother Charlie. Charlie is soon approached by Sheriff John Quincy Wydell and when the sheriff threatens him at gunpoint, Charlie agrees to help him catch the "Firefly's." When the sheriff catches the family, he takes them back to their ranch and decides to torture and kill them just as they had killed his brother George (in the first movie.) The sheriff staples Otis to a chair and leaves the two alone, he lights the house on fire. When he is taking Baby outside to kill her, Tiny appears and snaps the sheriffs neck. As Tiny goes in the house to die alone, Baby, Otis and Spalding escape in Charlie's car. The movie has graphic violence and nudity.