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- Developed by NeuroSearchNeuroSearch: Tesofensine
- Inhibits serotonine, dopamine and noradrenalineWashington Post: New Diet Pill... (October 22, 2008)
- Side effects include constipation, depression, high blood pressure and moreWashington Post: New Diet Pill... (October 22, 2008)
- Clinical tests will begin in 2009Washington Post: New Diet Pill... (October 22, 2008)
- Patients lost up to 12.8 kg in six months, according to initial testsWashington Post: New Diet Pill... (October 22, 2008)
- The drug is to be sold in American and European marketsNeuroSearch: Tesofensine
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Tesofensine is a drug that treats obesity by inhibiting several neurotransmitters in the brain, and subsequently suppressing appetite and hunger. According to early studies, the drug is twice as effective as Rimonabant.NeuroSearch: Tesofensine
The weight loss effects were discovered accidentally. The drug was first given to Alzheimer's and Parkinson's disease patients, who lost weight as the result. Further tests combined the drug with a low calorie diet.BBC News: Diet drug 'doubles weight loss' (October 22, 2008)
Side Effects
Side effects include increased heart rate and blood pressure, as well as reduced muscle mass. Doctors agree that the drug needs more testing and monitoring, because some of the side effects are potentially hazardous. "Additional study is needed," said one of the researchers.Washington Post: New Diet Pill... (October 22, 2008)

