Tasimelteon

Tasimelteon is an experimental drug that acts like the melatonin, and may have the ability to take the edge off jet lag. Melatonin is a hormone produced by the pineal gland.Vivo: The Pineal Gland and Melatonin It controls the body's sleep-wake cycle.Mayo Clinic: melatonin Tasimelteon is similar to melatonin in that it helps the body to regulate its sleep-wake cycle.

Researchers from Australia and the United States say that tasimelteon may be effective in reducing the symptoms of jet lag and sleep disorders such as those experienced by shift workers, by allowing users to maintain a deeper and longer sleep UPI: Tasimelteon May Cure Jet-lag

Research was conducted by Vanda Pharmaceuticals who published their findings in British medical journal, The Lancet.Pharmatimes: Vanda’s tasimelteon could provide a solution to jet lag

Tasimelteon could be available on the market for consumers with jet lag or sleep disorders within the next three years.

• "About two thirds of all international travelers who cross time zones experience jet lag symptoms, which include disruption of sleep, difficulty getting to and staying asleep, sleepiness during waking hours and gastrointestinal symptoms."
• "Our studies show that tasimelteon is able to effectively shift the rhythm of melatonin levels in the body, which are a well-established marker of the human biological clock."
• "This drug has the potential to improve the quality and quantity of sleep for patients with transient insomnia caused by jet lag."
• "Tasimelteon improved a patient's ability to fall asleep and then stay asleep when bedtime was shifted earlier by five hours. This is the equivalent of traveling eastwards and putting your clock back five hours, such as returning from India to Melbourne, or Dubai to Perth."
• "Our work has shown the drug to be highly potent, having the strongest effect when first taken; a single dose treatment was found to be effective for this type of sleep disturbance."
• Quotes from Dr. Shantha Rajaratnam, Monash University's School of Psychology, Psychiatry and Psychological Medicine Science Daily: New Medication Brings Hope Of Jet Lag Cure