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- May also be referred to as hemoglobin SS diseaseMedlinePlus: Sickle Cell Anemia
- Inherited blood disorderSickle Cell Disease Association of America: What is Sickle Cell Disease?
- Diagnosed by blood testMedlinePlus: Sickle Cell Anemia
- Approx. 70,000 people affected in U.S.National Heart Lung and Blood Institute (NHLBI): Sickle Cell Anemia: Key Points
- 1 in 12 African Americans carry sickle cell geneSickle Cell Foundation of Georgia: Sickle Cell Trait Fact Sheet
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Sickle cell anemia is an inherited blood disorder in which the body produces an abnormal variation of hemoglobin. The variation, called Hemoglobin S, produces short-lived, abnormally-shaped red blood cells The sickle shaped cells do not move easily through the blood vessels, which slows down blood flow and prevents blood from reaching various parts of the body. This can cause severe pain, serious infections and organ damage. The short lifespan of the cells (about 16 days) causes anemia. Sickle Cell Disease Association of America: What is Sickle Cell Disease?
Care and Treatment
Treatments might include medications such as antibiotics and anti-inflammatory medications. Other treatments such as blood transfusions, supplemental oxygen or possibly a bone marrow transplant may be recommended.Mayo Clinic: Lifestyle and Home Remedies Mayo Clinic: Treatments and Drugs National Heart Lung and Blood Institute (NHLBI): How Is Sickle Cell Anemia Diagnosed?Malaria
Researchers in the 1940's observed that patients with sickle cell anemia were more likely to survive malaria. It was discovered that the clumping of the blood cause by the sickle cell gene tended to enable the spleen to eliminate the malaria parasite.PBS: A Mutation StorySickle Cell Trait
It takes two genes for Hemoglobin S to cause sickle cell anemia. A person who has one gene is said to have sickle cell trait, in which the body produces both normal hemoglobin and Hemoglobin S. While not usually considered a disease, sickle cell trait can contribute to fatigue and has occasionally been cited as a contributing factor to exercise related sudden death.National Institutes of Health (NIH): Sickle Cell Disease - Inheritance Howard University: Sickle Cell Trait-
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Sickle Cell Anemia Questions
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What gene mutation causes Sickle Cell Anemia? 1 AnswerIt's a autosomal recessive mutation in the HBB gene. This gene codes for hemoglobin. No one knows precisely how it originally mutated. But it is now passed fr... read more -
How we know about Symptom of Sickle Cell Anaemia ? 4 AnswersUsually the symptoms of Sickle Cell Anemia can be seen on an infant when he is 4 months old. These are: 1. Periodic episodes of pain. 2. Swollen hands and fee... read more -
what is solar cell? 2 AnswersA solar cell is a device designed to take sunlight and convert it into electrical energy. However, it may also mean a device that simply captures the energy in... read more
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Sickle Cell Anemia Discussion and Blogs
- Sickle Cell Blog: Sickle Cell Can Kiss... (May 11, 2007)
- MedHelp: Sickle Cell Anemia Posts
- DailyStrength: Sickle Cell Anemia Discussions
- Biology Online: Sickle Cell Anemia
- Sickle Cell Society: Sickle Cell Anemia Forum
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