Purple Glove Syndrome

Purple glove syndrome is a skin disorder in which the extremities become swollen and painful and discolored.Unbound Medline: Incidence and consequence of purple glove syndrome (1998) The name of the disorder refers to the severe discoloration that results in the hands.Unbound Medline: Incidence and consequence of purple glove syndrome (1998) Purple glove syndrome has been seen as an adverse reaction to the anti-epileptic drug Phenytoin, an injectable form of Dilantin.WebMD: 20 Drugs the FDA Is Watching (September 5, 2008)

Purple glove syndrome is a result of leaking from the blood vessels.AAFP: Photo Quiz: Edema and Discoloration It is not known, however, exactly how the administration of Phenytoin can cause the leaking.AAFP: Photo Quiz: Edema and Discoloration