Macrophage

Categories: Health | Science & Mathematics | Biology | Anatomy Physiology

- Structure: Agranular, mononucleate cells containing lysozyme http://www.wisc-online.com/objects/index...
- Function: Removal of dead cells and foreign invaders http://www.medterms.com/script/main/art....
- Disorder: Leukemia, Reactive Langerhans cell disorders, and others http://www.ncbi.nlm.nih.gov/pubmed/75247...

White blood cells, or leukocytes, include a specialized type of cell called macrophages. They are produced as monocytes by stem cells in the bone marrow and they differentiate into either wandering macrophages or fixed macrophages. Both types of macrophages engulf (phagocytosis) and destroy dead cells and foreign invaders in the body, such as bacteria, protozoa and tumor cells. Fixed macrophages are found in especially vulnerable intracellular areas of the body, such as the lungs, intestines, and liver. When macrophages encounter and destroy foreign invaders they produce fragments which activate the acquired immune system.http://www.merck.com/mmpe/sec13/ch163/ch163a.html http://www.mansfield.ohio-state.edu/~sabedon/black16.htm http://courses.washington.edu/conj/bloodcells/phagocytosis.htm
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The content in this page is not a substitute for professional medical advice. If you need information about macrophages, please consult your doctor.

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  Macrophage - Wikipedia, the free encyclopedia
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- Macrophages: The home of macrophage biology - Home
  
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- macrophage: Definition from Answers.com
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- Definition of macrophage - NCI Dictionary of Cancer Terms
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Macrophage News
- Relapsing macrophage activating syndrome in a 15-year-old girl with Still's ...
  
  Case report: We describe a patient with SD who developed macrophage activating syndrome with ARDS requiring resuscitation and mechanical ventilation. ... (November 19, 2009)
  7thSpace Interactive (press release)
- Disparate oxidant gene expression of airway epithelium compared to alveolar ...
  
  The small airway epithelium and alveolar macrophages are exposed to oxidants in cigarette smoke leading to epithelial dysfunction and macrophage activation. ... (November 17, 2009)
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- MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional ...
  
  Upon transplantation, the expanded cells are nontumorigenic and contribute to functional macrophage populations in vivo. Small hairpin RNA inactivation ... (November 05, 2009)
  Science Magazine (subscription)
- Serum Amyloid P Inhibits Fibrosis Through FcγR-Dependent Monocyte-Macrophage ...
  
  ... of human serum amyloid P, regulated by activating Fcγ receptors, and dependent on inflammatory monocytes and macrophages, but not fibrocytes. ... (November 04, 2009)
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Macrophage Blogs
- Immunity - Macrophage- and Dendritic-Cell-Derived Interleukin-15 ...
  
  We showed that monocytes gave rise exclusively to CD103CXCR1 lamina propria DCs under the control of macrophage-colony-stimulating factor receptor (M-CSFR) and Fms-like thyrosine kinase 3 (Flt3) ligands. ... (November 19, 2009)
  cell.com
- Journal of Clinical Investigation -- Inflammatory macrophage ...
  
  After induction of peritonitis by thioglycollate injection, we found that Plg–/– mice displayed diminished macrophage trans-ECM migration and decreased MMP-9 activation. Furthermore, injection of the active form of MMP-9 in Plg–/– mi...
  jci.org
- CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose ...
  
  Conclusions—CCL5 could participate in the inflammation of obese WAT by recruiting blood monocytes and exerting antiapoptotic properties on WAT macrophages. This specific role of CCL5 on macrophage survival with maintenance of ... (November 05, 2009)
  atvb.ahajournals.org
- pubget—the blog: Hot off the presses! Nov 01 Nature medicine
  
  This increases autoantibody production and predisposes global and macrophage-specific Ppard-/- mice to autoimmune kidney disease, a phenotype resembling the human disease systemic lupus erythematosus. Thus, PPAR- has a pivotal role ... (November 26, 2009)
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- Macrophages and Dendritic Cells: Methods and Protocols (Methods in Molecular Biology) - $110.00
  
  Amazon.com: Macrophages and Dendritic Cells: Methods and Protocols (Methods in Molecular Biology) (9781588299727): Neil E. Reiner: Books
  
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- Macrophage Scavenger Receptor A Mediates Adhesion to Apolipoproteins A-I and E http://kele.es/lol
- "macrophage of smoker is distinguishable at first sight"
- mab-3f8 + granulocyte-macrophage colony-stimulating factor vs 13-cis-retinoic acid + gm-csf in primary refractory http://bit.ly/8Da5BR
- RT @masstext: omnomnom pathogens I'm a macrophage.
- #imthankfulfor biology , friends family, food, my apt, and my macrophage oh and what the heck my stupid landlord. >>
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