The ABC medical drama Grey's Anatomy follows surgical students in the fictional Seattle Grace Hospital through their internship and residency. They lean on, compete with, and become romantically entangled with each other.

• Ellen Pompeo as Dr. Meredith Grey
• Patrick Dempsey as Dr. Derek Shepherd
• Katherine Heigl as Dr. Isobel "Izzie" Stevens
• Sandra Oh as Dr. Cristina Yang
• T.R. Knight as Dr. George O'Malley
• Justin Chambers as Dr. Alex Karev
• James Pickens Jr as Dr. Richard Webber
• Chandra Wilson as Dr. Miranda Bailey
• Eric Dane as Dr. Mark Sloan
• Sara Ramirez as Dr. Callie Torres
• Chyler Leigh as Dr. Lexie Grey
• Brooke Smith as Dr. Erica Hahn
• Isaiah Washington as Dr. Preston Burke
• Kate Walsh as Dr. Addison Montgomery

• "Even with outrageous cases typical of every prime-time hospital series... Grey's Anatomy manages, with snark and sex appeal, to save itself from wonky patient-of-the-week sentimentality."—Entertainment WeeklyMetaCritic: Grey's Anatomy Season 1 DVD

• "The show not only features interesting medical cases but also an attractive, talented cast and plenty of sex and romance."—Los Angeles Times"MetaCritic: Grey's Anatomy Season 1 DVD