Grand Theft Auto: San Andreas Walkthrough

The time has come to finally take out the Ballas and all of your enemies once and for all. This is where it all ends.

Once you get a call from Sweet, start a gang war and increase your respect until Sweet calls you once more.
Sweet has learned the location of Smoke's hideout. Get in the car and get over to Big Smoke's Crack Fortress, marked by a yellow blip on your radar.
In order to obtain access, you'll need to break down the brick wall. For that, head to get the SWAT Tank, marked by a blue blip on your radar.
Now in the tank, go back to the Crack Fortress, marked by a yellow blip on the radar, and smash right through the wall on the corner. Continue in the tank and run over any Ballas in your way.
Enter through the yellow blip.
On the 1st floor, take out the guards at the top of the staircase and those hiding around the corner.
Around the next corner, take out the gang members down the long hallway. There's a body armor vest through the piping.
Through the swing doors to your right is a big, open warehouse. Take out all the guards inside, being sure to make use of the cover of the doors and ducking behind crates. The guards will hide behind the pillars and squat down on the deck upstairs.
Once you've cleared the room, exit through the opposite side and take care of the guards hiding behind the boxes. Up the stairs is another guard. Hang a right to follow the path to a heart for more health.
Now on floor 2, up the stairs is another guy waiting for you, along with a body armor vest.
The next set of swinging doors will open up into another wide open warehouse room. Aim for the red barrels to cause an explosion and take out multiple enemies at once. Again, many of the enemies will duck for cover and hide on the next floor up.
Head upstairs and take out any enemies in your way. Through the swinging doors at the end of the hallway is a room with another heart. Use it if you need it.
Now on the 3rd floor, you know the routine. Guys will be waiting for you at the top of the stairs. Kill them and take the body armor.
To your right, you will now be in a nicely furnished penthouse location. Take out the guards in your way and make your way through the rooms, being sure to take out any guards so they don't sneak up on you.
Move past the Big Smoke statue and use the pillars as cover if necessary.
Make a left into the stripper room for another body armor vest.
If you follow the path along and up the stairs, you'll come into Smoke's main room.
Watch the cutscene of him playing video games. When you take control, it's time to kill Smoke. He's wearing body armor, so you'll need to attempt to target other parts of his body.
Head upstairs if you need more health. Kill any guards that attempt to shoot at you while you battle Smoke.
In the north east corner of the room are the thermal goggles. Use them to see in the dark and finish off Smoke.
With Smoke dead, Tenpenny shows up to settle his score. He sets the building on fire and now you have to escape.
Use the night vision goggles to see in the dark and make your way back out through the building, killing anyone in your path.
When you reach the next floor down, you'll begin to see the smoke from the fire. Grab the fire extinguisher and keep it handy. As your make way through the remainder of the level, kill any enemies before you attempt to extinguish the fires blocking your path.
Use the body armor vests, located in the same location as when you first climbed the stairs, if you need more protection.
Once you reach the main exit, CJ will make a daring escape as the building explodes behind him. Sweet will jump onto the back of Tenpenny's fire truck, grasping onto the ladder chute as the truck speeds away. Take control of the car and drive to stay as close to the dangling Sweet as you can. Do not attempt to ram the truck or harm it.
Maintain your speed and stay in a safe position for Sweet to finally drop down into your car.
Once Sweet drops in, he'll take control of driving. Now that you're in the passenger seat, fire at the police officers climbing on the ladder toward you.
Gang members will begin trying to attack you by vehicle and on foot. Keep a keen eye and kill any that come close to you.
Shoot out the charging police cars.
Continue shooting at the fire truck to kill Tenpenny. Eventually, he'll lose control and go soaring off a bridge. Watch the cutscene and enjoy the finale. Congratulations, you've just beaten Grand Theft Auto: San Andreas.