Ghostbusters Sanctum of Slime is an action video games developed by Behaviour Interactive and published by Atari. The game was releaed for download on Xbox 360, Playstation 3 and PC on March 23, 2011. The game features a solo campaign that can also be played with four player in a cooperative mode.

Ghostbusters Sanctum of Slime is inspired by the series of film Ghostbusters released on 1984 and 1989, staring Bill Murray and Dan Aykroyd. The game and the films are telling the story of a group of ghost hunters protecting the city of New-York from a ghost invasion.

Alan, Bridget, Gabriel and Samuel are the four members of the Ghostbusters, a team of hunters specialized in ghosts. They wander in New-York city looking for the presence of ghosts and monsters, hidden in the dark places of the town. They are now facing a huge wave of ghosts and have to defeat Dumazu the Destroyer who intends to take control of the planet.

Four characters can be chosen to play Ghostbusters Sanctum of Slime and the campaign can be played either on solo or cooperative mode. The player has to fight ghosts in levels divided in section where the enemies appear. Three weapons can be selected: red, yellow and blue, and each of them is effective against an enemy of the same colour. A boss is waiting at the end of each levels. Two levels of the game are played on the top of the Ghostbusters' truck and the player has to shoot at the enemies while riding in the city.

• Hero (10) – Revive any teammate 20 times.
• Speed Demon (15) – Get 100% score with the trap.
• Story Teller (20) – Watch each comic without skipping.
• Rookies (10) – Finish the first level.
• Bustin’ Makes Me Feel Good (10) – Unlock every level and defeat the final boss.
• Nice Thinking, Ray (10) -Find all the hidden collectibles.
• Full House (20) – Finish an online level with the help of 3 other players.
• Rush Hour Revenge (20) – Defeat the Subway Smasher.
• Don’t Touch the Car (40) – Finish a chase level with at least 75% of the Ecto-shield up.
• Team of Four (15) – Play with each character.
• Rockstar (10) – Destroy all the expensive LCD televisions in the hotel.
• Colorblind (20) – Kill a Slime Abomination with the wrong weapon.