In 2004, Eads, along with co-star Jorja Fox, were allegedly fired over contract disputes. A week later the dispute was settled and both stars were rehired.

Some of Eads other film and television credits are Evel Knievel, Monte Walsh, The Spring, Dust to Dust, Two and a Half Men, ER and Strangeluck.

1. "I think people like to solve puzzles. I think when they tune to the show ... they feel like they're really learning something. It seems like in this day and age, with computers, the TV's become more than just this "boob tube": people can tune in, learn something and have a good time." — George Eads on CSI's success
2. "I add things (to scenes), so does everybody. We get it from Billy. Billy is the king of adding things to scenes. He's a great guy." — George Eads on William Petersen
3. "I was going to play the exact same look, the exact same hairstyle for as long as the show went. And then I was late for work and got fired, and that made me mad, so I shaved my head." — George Eads on shaving his head
4. "I think people would be suprised at how much we curse when we screw up. I'm like somebody with Tourette's Syndrome." — George Eads on swearing on set
5. "Many forms, sizes and colors, I think there are heroes in sports, in life...It would be cliché to say my dad, my granddad. I think I'm a fan of people who were brave, my aunt, my grandmother, those are my heroes." — George Eads on heroes