The Final Four is one of the most prominent events in college sports, and as such, predicting the teams that will be in the Final Four and ultimately win the NCAA tournament is a common practice for sports fans and gamblers alike.

Final Four predictions can come both before and after the competing teams are announced and are often released by major media outlets like ESPN, CBS Sports and Sports Illustrated. Similarly, a number of celebrities will release their picks, most commonly actors and other personalities that work for CBS, the official home for all March Madness broadcasts. President Barack Obama, who is a big NCAA Basketball fan, has also released his predictions and picks in the past.

In the 2010 NCAA Men's Basketball Tournament, the Final Four was played at Lucas Oil Stadium in Indianapolis, Indiana, from April 3 to April 5, 2010. The teams competing in March Madness 2010 were named on Selection Sunday, March 14, 2010.

Prior to the season, Dick Vitale released his Final Four predictions, which included Kansas, Kentucky, Duke and Michigan State.c

• Gary Parrish:
  • Kansas over Kentucky for the title, Syracuse and Baylor in the Final Fourc

• Gregg Doyel:
  • Kansas over West Virginia for the title, Duke and Syracuse in the Final Fourc

• Brian De Los Santos:
  • Kansas over Kentucky for the title, Syracuse and Duke in the Final Fourc

• Michael Freeman:
  • Kansas over Kentucky for the title, Duke and Pittsburgh in the Final Fourc

• Greg Anthony:
  • Kansas over West Virginia for the title, Syracuse and Villanova in the Final Four

• Dan Wetzel:
  • Kansas over Kentucky for the title, Syracuse and Villanova in the Final Fourc

• Jason King:
  • Kansas over Kentucky for the title, Syracuse and Baylor in the Final Fourc

• Gerry Ahern:
  • Kentucky over Kansas for the title, Kansas State and Villanova in the Final Fourc

• Mike Hugeunin:
  • Kansas over Kentucky for the title, Syracuse and Villanova in the Final Fourc