Fallout 3 Bosses

There are not any official bosses in the game, Fallout 3, though there are creatures, such as the five Super Mutant Behemoths in the game, which are boss-like in nature.GameSpy: Planet Fallout Fallout 3 Wiki: Super Mutant Behemoths

The strongest of the Mutants, the Behemoths are huge, reaching 30 feet in height and typically carrying a shopping basket of human limbs on their backs. Strategies for taking down these creatures include using bottle cap mines to cripple their legs while shooting them with the Fatman or the Minigun. Their hit points are estimated to be around 2500 and they often drop many high quality items upon defeat. There are 5 Behemoths scattered throughout the game and there is an achievement for killing all of them.GameSpy: Planet Fallout Fallout 3 Wiki: Super Mutant Behemoths

The Fallout franchise of videogames has been around since 1997, when the first game, developed by Black Isle Studios, was released. Positive response to the first game, led to the quick creation of a sequel. All three of the games are set in an alternative version of a post-apocalyptic United States. The first two games were played in an overhead view and had turn-based combat. Every action you did would alter your stats. Fallout 3 maintains the roots of the series, but has updated the game for the current generation of consoles. The world is now fully 3D and combat can happen in real time like a traditional first-person shooter, or by using the V.A.T.S. targeting system. Your stats are also still affected by your actions, giving you the opportunity to play the game as a good guy or a bad guy.MyCheats: Fallout 3 Superguide