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• The powerful anti-tumor necrosis factor Enbrel is a drug prescribed for the treatment of rheumatoid arthritis.

  Additionally, Enbrel is showing promise for treating Alzheimer's disease. While it is currently not being prescribed for such purposes in the United States and further studies are necessary, doctors in Australia are prescribing it off-label for Alzheimer's disease.FOXNews: Arthritis Drug Shows Promise in Reversing Symptoms of... (January 10, 2008)

• Fast Facts

  1. Generic name: Etanercept
  2. FDA approved: 1998
  3. Manufacturers: Amgen, Wyeth
  4. Class: Tumor necrosis factor blocker
  5. Use: Rheumatoid arthritis
  6. Potential use: Alzheimer's disease
  7. Route: Subcutaneous

• Side Effects

  • Headache
  • Nausea
  • Butterfly rash
  • Swelling of arms andlegs
  • Dizziness
  • Hair loss

• Serious Interactions

  • Abatacept
  • Anakinra
  • Live vaccines

• FDA Warning

  On September 4, 2008, the Food and Drug Administration (FDA) in the United States issued a warning in regards to reports of histoplasmosis in patients being treated with Enbrel. Other tumor necrosis factor blockers, such as Cimzia, Remicade and Humira, were also included in the FDA warning issued.FDA News: Manufacturers of TNF-Blocker Drugs Must Highlight Risk... (September 4, 2008)

• Enbrel and Alzheimer's Disease

  Researchers are finding that an elevated level of the tumor necrosis factor-alpha (TNF-alpha) may be a key component in the development of Alzheimer's disease. Therefore, since Enbrel inhibits TNF, it has the potential to treat Alzheimer's disease.Journal of Neuroinflammation: Rapid cognitive improvement in Alzheimer's disease... (January 9, 2008)

• Disclaimer

  This page is not a substitute for medical advice. Please consult your doctor for further information about Enbrel.

• Related Pages on Mahalo

  Arthritis | Rheumatoid Arthritis | Alzheimer's Disease | Wyeth Pharmaceuticals | Cimzia | Amgen | Remicade | Humira

• Related Mahalo Pages

  Alzheimer's Disease | Dementia | Rheumatoid Arthritis | Wyeth Pharmaceuticals

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