Like every other game for Xbox 360 consoles, Duke Nukem 3D, available for download via XBLA, has a series of achievements. Completing each achievement adds to players' Gamer Scores. While achievements are earned by completing specific tasks in the game, they do not affect the outcome of the game itself. This is the first time a Duke Nukem game has contained achievements.

1. Piece of Cake (25 points): Complete "L.A. Meltdown" on any difficulty or in co-op.

2. Let's Rock (25 points): Complete "Lunar Apocalypse" on any difficulty or in co-op.

3. Come Get Some (25 points): Complete "Shrapnel City" on any difficulty or in co-op.

4. Game Over (25 points): Complete "The Birth" on any difficulty or in co-op.

5. Duke's Mighty Foot (10 points): Step on 40 enemies after using the Shrinker on them.

6. Looks Like Cleanup on Aisle 4 (10 points): Step in a pile of excrements.

7. Shake It Baby (10 points): Tip an exotic dancer.

8. Oomph, Uugh, Where is it? (10 points): Find 70 secret areas.

9. Alien Maggots are Gonna Pay (10 points): Finish the "Hollywood Holocaust" level in under 3 minutes.

10. Gonna Rip Em' a New One (10 points): Get 100 total kills in ranked Dukematch games (Online).

11. See You in Hell (15 points): Get 250 total kills in ranked Dukematch games (Online).

12. Hail to the King, Baby (25 points): Earn respect and get 500 total kills in ranked Dukematch games (Online).