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- Ingredient in: Unisom, NyQuil
- Class: Antihistamine
- Available over-the-counter
- Use: Short-term insomnia
- Alternative Use: Morning Sickness with Vitamin B6,
- Should not be given to children under 12
- Take 30 min before bedtime
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Doxylamine is an antihistamine that causes drowsiness. On its own, doxylamine is used as a short-term treatment for insomnia. Doxylamine is also often present in various cough and cold medicines.
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Mode of Action
Doxylamine works by inhibiting the body's allergic response system, which is regulated through histamine.MedlinePlus: DoxylamineControversy
Although not the sole determinant for his death, doxylamine was one of the drugs in Heath Ledger's system when he died.Wired: Unnecessarily Dangerous Drug Combo Caused Heath Ledger's Death (February 6, 2008)-
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Doxylamine Controversy
- FOXNews.com: Drugs That Killed Heath Ledger Could Be in Your Home (February 6, 2008)

