Death Jr II: Root of Evil Wii is an action-adventure game for the Nintendo Wii. It was developed by Backbone Entertainment and published by Eidos Interactive. The game was previously released on the Sony PlayStation Portable in October of 2006.

In Death Jr II: Root of Evil Wii, the player takes on the role of the Grimm Reaper's son, Death Jr. He and his friend Pandora have collected a cocoon for their school biology project. While arguing, it releases an evil spirit called Furi. Death Jr. and Pandora, along with their friends, must fight to put a stop to Furi and his minions.

Death Jr II: Root of Evil Wii is set in a humorous world that puts Death Jr. and Pandora against the enemy spirit Furi. The game can be played alone or with someone else in co-operative play. The game consists of 19 levels and features over 60 different enemies. The game itself is a platform style game, but features 3D environments. There are a variety of weapons to chose from, ranging from the reaper's scythe to C4 hamsters. The game also allows multiple moves that the characters can unlock as the game progresses.