Dead Space, which was released for PS3, Xbox 360 and PC on October 14, 2008, contains a large cast characters, but focuses primarily on the main character and his support team.

Dead Space features a cast of characters with the main protagonist being Isaac Clarke, a systems engineer who ventures into an infested spaceship to find his missing girlfriend, Nicole.Yahoo!: Dead Space Preview Other characters include the two people that Isaac arrives at the spaceship with - technology expert Kendra Daniels and the militaristic Zach Hammond. Isaac gets separated from his partners and must find his way to reunite with them and escape. Other characters include Doctor Kyne, who will be voiced by horror film director Dario Argento in the Italian version of Dead Space.1up.com: Dario Argento Adds Chills to Dead Space (September 26, 2008)