As with any Essential Oils, Clove oil should be tested for topical use on a small patch of skin (preferably the inside of the forearm as it tends to be a good indicator of skin sensitivity) before using the oil (straight or diluted) on larger areas. Essential Oils, especially strong ones like clove or Cinnamon Essential Oil, are usually diluted in a Carrier Oil for topical use.

If the area being treated topically becomes too warm or begins to feel as though it is burning, dilution with carrier oil should begin immediately. Generally, washing with soap and water will not remove oils well, while washing with or dilution with a carrier oil will relieve the burning sensation more quickly. Avoid getting Clove Essential Oil or any Essential Oils directly on mucous membranes or in eyes or ears.

Eugenol, a major constituent in Clove Essential Oil, is a substituted phenol compound which is water and oil soluble. Eugenol is the component which provides Clove Oil with most of its properties. In addition to other uses, Clove oil has been used, successfully, as an insect repellent. Some studies indicate that Clove oil, taken diluted internally on a regular basis, may help reduce blood sugar levels and help in balancing insulin production.