The San Diego Chargers and the New Orleans Saints met in London for a regular season National Football League game on October 26, 2008. The Saints defeated the Chargers 37 to 32 at Wembley Stadium.NFL.com: Chargers, Saints to play in London in 2008

In 2005, the NFL played its first game outside of the United States when the San Francisco 49ers and Arizona Cardinals played in Mexico City. An annual London game at Wembley Stadium was introduced in 2007. In the first Wembley game, the New York Giants defeated the Miami Dolphins on October 28, 2007, in front of 81,176 people. The NFL London game is scheduled to continue as an annual event through 2011.NFL.com: Chargers, Saints to play in London in 2008 The Buffalo Bills also play an annual game in Toronto.