Britney Spears performed with Madonna during a stop on Madonna's Sticky & Sweet Tour at Dodger Stadium in Los Angeles. Spears sang with Madonna on the song "Human Nature".USAToday: Britney, Justin back up Madonna at L.A. concert (November 7, 2008)

Justin Timberlake also performed with Madonna on the same evening. It was rumored that Spears and Timblerlake would be performing together. However, Timberlake appeared on stage with Madonna almost an hour after Spears was on stage. Timberlake and Madonna performed their duet from Hard Candy, "Four Minutes".USAToday: Britney, Justin back up Madonna at L.A. concert (November 7, 2008)

The Sticky & Sweet Tour began on May 16, 2008 at Millennium Stadium in Cardiff, Wales. Madonna is touring in support of her most recent album, Hard Candy.