Blake DeWitt calls Sikeston, Missouri his home. On November 20, 2008, he was the featured speaker at the Sikeston Area Chamber of Commerce's November lunch meeting, it was here that he was presented a key to the city by Mayor Mike Marshall and learned that his No. 6 would be retired by the Sikeston High School baseball team in the spring of 2009. Mayor Marshall even went as far as to declare April 2008 in Sikeston as "Blake DeWitt Month."

Perfect Game USA rated DeWitt as the No. 2 prospect in Missouri after his junior season at Sikeston High School and was named a Baseball America First-Team All-American after his senior season, hitting .558 with 15 home runs and 48 RBI. He intended on playing baseball at Georgia Tech, going as far as signing a letter of intent but instead signed with the Los Angeles Dodgers after being selected 28th overall in the 2004 draft. http://losangeles.dodgers.mlb.com/team/player.jsp?player_id=455088

DeWitt was named the everyday third baseman during spring training by Joe Torre this year. In 21 games this season, he is batting .297 with 8 RBI's, and 0 home runs. On May 2nd, DeWitt had his best game of the season going 4-4 wiith 2 doubles and 3 RBI's. http://dodgers.mlb.com/mlb/fantasy/wsfb/news/index.jsp?action=locate&pid=455088 http://losangeles.dodgers.mlb.com/team/player.jsp?player_id=455088

In 2009, DeWitt Made Dodgers' Opening Day roster and was called up from the minor leagues six different occasions. Of the 31 games he was called up for, he made six starts, five at third base and one at shortstop, batting .204 with two home runs and four Runs Batted In. He hit his first career pinch-hit home run on July 7 at New York and his second on September 19 vs. San Francisco. The two pinch-hit homers tied him for third in the National League behind Matt Stairs' five and Chad Tracy's three. Back in the minor leagues, he hit .256 with seven homers and 47 RBI in 92 games for Triple-A Albuquerque.http://losangeles.dodgers.mlb.com/team/player.jsp?player_id=455088

Beginning the 2008 year in Spring Training in minor league camp, DeWitt went on to be the Dodgers' Opening Day third baseman and hit .264 with 9 homers and 52 RBI in 117 games. He joined the team on March 8 after injuries sidelined both Nomar Garciaparra and Andy LaRoche. Among National League rookies, ranked sixth in average and was tied for fourth in RBI also ranked sixth with 45 runs scored and 97 hits, and was tied for eighth with 24 extra-base hits. In May he was named National League Rookie of the Month, hitting .322 with five homers, 18 RBI, and 14 runs scored in 26 games. He was optioned back to Triple-A Vegas when Casey Blake was acquired from the Cleveland Indians.

In the post-season he started all eight of the Dodgers' postseason games at second base. He batted .167 overall, going 3-for-11 with 2 doubles and an RBI in the three-game sweep of the Cubs in the National League Division Series and 1-for-13 with a triple and 5 RBI in five games of the National League Championship Series against the Phillies.http://losangeles.dodgers.mlb.com/team/player.jsp?player_id=455088