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Your peripheral nerves. These nerves extend from your spinal cord to your skin, muscles, bones, joints and internal organs. Some peripheral nerve fibers end with receptors that respond to touch, pressure, vibration, cold and warmth. Other types of nerve fibers end with nociceptors (no-sih-SEP-turs) — which are receptors that detect actual or potential tissue damage.
Nociceptors are most concentrated in areas prone to injury, such as your fingers and toes. When nociceptors detect a potentially harmful stimulus — such as the hard surface that stubbed your toe — they relay pain messages in the form of electrical impulses along a peripheral nerve to your spinal cord and brain. Sensations of severe pain are transmitted almost instantaneously.
Nociceptors are most concentrated in areas prone to injury, such as your fingers and toes. When nociceptors detect a potentially harmful stimulus — such as the hard surface that stubbed your toe — they relay pain messages in the form of electrical impulses along a peripheral nerve to your spinal cord and brain. Sensations of severe pain are transmitted almost instantaneously.
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Please include a source for your answer.
http://en.wikipedia.org/wiki/Pain