What is the most important thing that happened in history on January 22?
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Information obtain from these two sites
http://www.thisdaythatyear.com/jan/events22.htm
http://en.wikipedia.org/wiki/1520s_in_England
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1528
22 January - Henry VIII and Francis I of France declare war on Emperor Charles V.1
March - trade suspended between England and the Netherlands because of the war with the Holy Roman Empire.1
June - Unrest in England caused by economic difficulties due to the war forces the government to seek a truce with the Empire.1
July - Major outbreak of sweating sickness in London.2
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Information quoted from http://en.wikipedia.org/wiki/1520s_in_England
This war was waged against Charles V, Holy Roman Emperor "his realm, which has been described as one in which the sun never sets, spanned almost 4 million square kilometers." Franis was defeated which prevented him from regaining his hold on Italy.Charles V was able to expand the Spanish empire in the New World which included Italy.
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