2 years, 3 months ago
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What is the best treatment for stage 1B uterine sarcoma?
Will a patient with the above diagnosis need radiation only or would chemo add to survial rate?
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M$1 Answer
DEFINITION
---quote---
A uterine sarcoma is a malignant tumor that arises from the smooth muscle or connective tissue of the uterus. If the lesion originates from the stroma of the uterine lining it is an endometrial stromal sarcoma, and if the uterine muscle cell is the originator the tumor is a uterine leiomyosarcoma. A lesion that also contains malignant tumor cells of epithelial origin is termed uterine carcinosarcoma (formerly called malignant mixed mesodermal/mullerian tumor).
---/quote---
source:
http://en.wikipedia.org/wiki/Uterine_sarcoma
STAGES
Stages of Uterine Sarcoma:
---quote---
- Stage IA: tumor is limited to the endometrium
- Stage IB: invasion of less than half the myometrium
- Stage IC: invasion of more than half the myometrium
- Stage IIA: endocervical glandular involvement only
- Stage IIB: cervical stromal invasion
- Stage IIIA: tumor invades serosa or adnexa, or malignant peritoneal cytology
- Stage IIIB: vaginal metastasis
- Stage IIIC: metastasis to pelvic or para-aortic lymph nodes
- Stage IVA: invasion of the bladder or bowel
- Stage IVB: distant metastasis, including intraabdominal or inguinal lymph nodes
---/quote---
source:
http://en.wikipedia.org/wiki/Uterine_sarcoma
TREATMENT OF STAGE IA, IB, IC
Treatment of stage I uterine sarcoma:
---quote---
- Surgery (total abdominal hysterectomy, bilateral salpingo-oophorectomy, and lymphadenectomy).
- Surgery followed by radiation therapy to the pelvis.
- Surgery followed by chemotherapy.
---/quote---
http://www.cancer.gov/cancertopics/pdq/treatment/uterinesarcoma/Patient/page5
WHAT IS RADIATION THERAPY ?
Radiation therapy is the medial use of ionizing radiation as part of cancer treatment to control malignant cells.
source:
http://en.wikipedia.org/wiki/Radiation_therapy
WHAT IS A CHEMOTHERAPY ?
---quote---
Chemotherapy, in its most general sense, is the treatment of disease by chemicals1 especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen. In its non-oncological use, the term may also refer to antibiotics (antibacterial chemotherapy).
---/quote---
source:
http://en.wikipedia.org/wiki/Chemotherapy
---quote---
A uterine sarcoma is a malignant tumor that arises from the smooth muscle or connective tissue of the uterus. If the lesion originates from the stroma of the uterine lining it is an endometrial stromal sarcoma, and if the uterine muscle cell is the originator the tumor is a uterine leiomyosarcoma. A lesion that also contains malignant tumor cells of epithelial origin is termed uterine carcinosarcoma (formerly called malignant mixed mesodermal/mullerian tumor).
---/quote---
source:
http://en.wikipedia.org/wiki/Uterine_sarcoma
STAGES
Stages of Uterine Sarcoma:
---quote---
- Stage IA: tumor is limited to the endometrium
- Stage IB: invasion of less than half the myometrium
- Stage IC: invasion of more than half the myometrium
- Stage IIA: endocervical glandular involvement only
- Stage IIB: cervical stromal invasion
- Stage IIIA: tumor invades serosa or adnexa, or malignant peritoneal cytology
- Stage IIIB: vaginal metastasis
- Stage IIIC: metastasis to pelvic or para-aortic lymph nodes
- Stage IVA: invasion of the bladder or bowel
- Stage IVB: distant metastasis, including intraabdominal or inguinal lymph nodes
---/quote---
source:
http://en.wikipedia.org/wiki/Uterine_sarcoma
TREATMENT OF STAGE IA, IB, IC
Treatment of stage I uterine sarcoma:
---quote---
- Surgery (total abdominal hysterectomy, bilateral salpingo-oophorectomy, and lymphadenectomy).
- Surgery followed by radiation therapy to the pelvis.
- Surgery followed by chemotherapy.
---/quote---
http://www.cancer.gov/cancertopics/pdq/treatment/uterinesarcoma/Patient/page5
WHAT IS RADIATION THERAPY ?
Radiation therapy is the medial use of ionizing radiation as part of cancer treatment to control malignant cells.
source:
http://en.wikipedia.org/wiki/Radiation_therapy
WHAT IS A CHEMOTHERAPY ?
---quote---
Chemotherapy, in its most general sense, is the treatment of disease by chemicals1 especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen. In its non-oncological use, the term may also refer to antibiotics (antibacterial chemotherapy).
---/quote---
source:
http://en.wikipedia.org/wiki/Chemotherapy
You can leave an optional "tip" with Mahalo's virtual currency, Mahalo Dollars. If you are asking a difficult question that might require some research, or if you'd like a wide variety of feedback, a higher tip often leads to more answers to your question.
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