What can you tell me about the drug "Septra"? Have you ever had to take it and if you did what kind of experience did you have using it?
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M$3 Answers
Generic name: Trimethoprim, Sulfamethoxazole. Brand names: Septra, Cotrima, Bactrim.
Co-trimoxazole was once a miracle medicine, due to its two ingredients: Trimethoprim and Sulfamethoxazole. Alone Trimethoprim and Sulfamethoxazole are bacteriostatic (inhibit the growth of bacteria, but do not kill the bacteria). When this two ingredients combines in a ratio of 1:5 (trimethoprim 1% & sulphomethoxazole 5 %), the results is an exception and miracle (bactericidal action, i.e., directly kills the bacteria). There is no other antibiotic or chemotherapy having this miracle properties. For this reason the old co-trimoxazole is still moving as GOLD medicine.
I have several times in several occasion taken Septra tablet (2 tabs twice daily). My doctor advised me to take adequate fluid (additional 5 glass fluids per day during the treatment for five days). If you take adequate fluid during Septra treatment, I think your experience will be better than me.
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Most important FACTS about SEPTRA:
Sulfamethoxazole, an ingredient in Bactrim, is one of a group of drugs called sulfonamides, which prevent the growth of bacteria in the body. Rare but sometimes fatal reactions have occurred with use of sulfonamides. These reactions include Stevens-Johnson syndrome (severe eruptions around the mouth, anus, or eyes), progressive disintegration of the outer layer of the skin, sudden and severe liver damage, a severe blood disorder (agranulocytosis), and a lack of red and white blood cells because of a bone marrow disorder.
Notify your doctor at the first sign of an adverse reaction such as skin rash, sore throat, fever, joint pain, cough, shortness of breath, abnormal skin paleness, reddish or purplish skin spots, or yellowing of the skin or whites of the eyes.
Frequent blood counts by a doctor are recommended for patients taking sulfonamide drugs.
What SIDE EFFECTS may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Bactrim.
• Side effects may include:
Hives, lack or loss of appetite, nausea, skin rash, vomiting
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: dofetilide, methenamine. If you are currently using any of these medications tell your doctor or pharmacist before starting sulfamethoxazole with trimethoprim. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: certain anti-diabetic medications (e.g., glipizide, glyburide, tolbutamide), "blood thinners" (e.g., warfarin), cyclosporine, digoxin, drugs which can increase potassium levels (e.g., ACE inhibitors such as captopril, lisinopril), hydantoins (e.g.,phenytoin), live vaccines, methotrexate, oral PABA, procainamide, pyrimethamine, tricyclic antidepressants, certain "water pills" (thiazide diuretics such ashydrochlorothiazide). This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.
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http://www.drugs.com/pdr/septra.html
http://www.medicinenet.com/sulfamethoxazole_with_trimethoprim-_oral/article.htm
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M$
Hi. My husband was prescribed APO-SULFATRIM DS800/160MG on Jan 22/04 for a possible urinary infection. A few hours after taking just one dose, he developed chills, sore achy joints, very bloodshot eyes, and a severe headache. Virtually incapacitated by what we thought was the onset of the flu, this normally healthy man was bed-ridden. Approximately 24 hours after taking that first dose, he requested that I take him to the hospital. The doctor immediately put him on IV fluids and tried to treat the main source of his discomfort - the blinding headache. They weren't really sure what was causing the problem. A few hours later, after administering a IV painkiller, he was well enough to go home. The doctor scheduled a CAT scan as a follow-up and also suggested not taking any more of Sulfatrim until feeling better, then trying again. This is what he did. A few hours after taking the pill the same symptoms appeared. So we could now conclude that this was the source. Needless to say, he did not, and will not take this drug again. He still has a residual headache from time to time (very rare for him before). After reading the fatal reactions that others have had, we were thankful that it wasn't worse.
BACTRIM: 19 February 2004
I just got home from a 3 day hospital stay with my husband. He saw a vascular doctor, dermatologist and infectious disease doctor. They are saying he had a reaction to Bactrim. His toes turned blue and his penis has pus and skin like burns on it. Just wonder if you have seen these symptoms before. The doctor said it was a good thing he sought help or he could have died. He has been through tons of blood tests, cultures, sonograms, etc. to try and figure out what this was. He took Bactrim only for a sinus infection and a day later, his toes were blood red and very painful. A few days, his penis became involved. What an ordeal!
Susan C.
Who for any reason wants a BLUE PENIS????
Don't do it, there are so many alternative holistic cures...
look into The PDR Family Guide to Natural Medicines & Healing Therapies (Pdr Family Guide to Natural Medicines and Healing Therapies)
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Thats awful !!! And I do even want to see a BLUE PENIS !! ok well the reason I asked this is because my doctor put me on the Septra because he thought I might have MRSA, I started taking the drug on Saturday and by Wed. I could not stay awake and I felt very ill. I left work that day early and called in on Thursday, (which I might not even have a job come Monday, because we had several catering jobs that day I called in). I have had flu like sysptoms every since (still do and this is Saturday). I can not eat or drink anything without it coming right back up (thank God my bathroom is right across from my bedroom), If I still feel this way Monday Iam going to my doctor because my heart rate seems to keep fluttering. I am glad all is ok with your hubby now !!
It has a specific schedule and certain foods, herbal and vitamins can have an effect making the drug literally not work. This combination of negation is called concomitant.
Septra must be taken full as prescribed or you run the risk of developing an antibiotic strain that is resistant to the drug.
Here is a good resource to learn more about the medication.
http://www.webmd.com/drugs/drug-15726-Septra+DS+Oral.aspx?drugid=15726&drugname=Septra+DS+Oral
I had taken it when i was very sick with penumocystis pneumonia. And it did work well. But I avoided grapefruit juice and anything else that was very acidic so it would work better.
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