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3 years, 2 months ago

What are the uses of proteins produced by transgenic bacteria?

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seshankrishnan | 3 years, 2 months ago
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Many useful human proteins are now synthesized by transgenic bacteria. Some of these are listed below.

Human growth hormone is used to treat dwarfism. It previously took the pituitary glands from over 50 cadavers to make one dose.

Human Insulin is used to treat diabetes. Insulin was previously obtained from the pancreas of slaughtered cattle and pigs. It sometimes caused allergic reactions.

Tissue plasminogen activator dissolves blood clots in heart attack victims.

Clotting factor VIII will soon be available. Most cases of hemophilia are due to the absence of this factor.

Human lung surfactant is used in premature infants with respiratory distress syndrome.

Atrial natriuretic hormone can be used to treat hypertension.

Bovine growth hormone (bGH) increases milk production in cows by about 10%.

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nushka | 3 years, 2 months ago Report

Excellent answer.
In research it is very common to produce the desired protein in a bacteria because it is much easier to purify it than it is from the original source. It is also useful to produce fusion and truncated proteins.

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