I'm a sound engineer by trade so I'll try to leverage that here. It really depends on what kind of podcasting you want to do. Leo Laporte does love the Plantronics mic. Some alternatives though:

Give a listen to the PC Gamer Podcast.
http://www.pcgamerpodcast.com/

They do a multiple person podcast using Skype and they wear and use the Steel Series headsets. They are comfy, have pull-out microphones (which sound pretty darn good), and are still great sounding headsets in their own right.
http://www.steelseries.com/us/products/audio

If you want to go the more traditional single microphone route I recommend a USB microphone solution. This removes the need for a mixing board and all that cabling.

From Samson (I recommend this one heartily): http://www.samsontech.com/products/productpage.cfm?prodID=1810

From Blue (These guys make amazing sounding microphones)
http://www.bluemic.com/products/Snowball

What kind of audio editing software do you have? What's the podcast about? I'd be happy to help you with a more custom solution to your needs. If you have any other questions send me a direct message and I can give you more specific answers.
Source(s):
http://www.pcgamerpodcast.com
http://www.steelseries.com/us/products/audio
http://www.samsontech.com/products/productpage.cfm?prodID=1810
http://www.bluemic.com/products/Snowball

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