This is a complete achievement list for Prototype on Xbox 360.

Revenge Revisited - 60
Complete Story Mode on hard difficulty.

Endless Hunger - 10
Consume 200 characters to boost your health.

Trail Of Corpses - 30
Kill 53,596 infected.

Wrecking Yard - 20
Destroy 2,000 vehicles.

Misconception - 20
Destroy 25 Infected Water Towers before they hatch.

Brain Trust - 20
Complete all Consume Events.

Streetwise - 50
Collect all Landmark collectibles scattered across New York City.

Polymath - 40
Collect all Hint Collectibles scattered across New York City.

Half-Truths - 10
Complete a mission without causing a single Military Alert.

Mankind Is Your Mask - 40
Complete 3 missions without causing a single Military Alert.

The Butcher - 30
Kill 50 characters in 5 seconds.

Return Fire - 10
Catch any object tossed by a Hydra; and throw it back.

Gunning - 10
Destroy 20 Helicopters in a single Helicopter flight.

Cleanup - 10
Kill 15 characters with a single Whipfist attack.

The First Thread - 10
Unlock the Web of Intrigue.

Self-Deception - 20
Discover what happened to Alex Mercer through the Web of Intrigue.

Web Of Knowledge - 60
Acquire all nodes of the Web of Intrigue.

It's Him! - 10
Patsy 5 military personnel.

In Plain Sight - 10
Evade 10 strike teams.

Infiltrator - 20
Infiltrate 10 Military Bases disguised as a Commander.

Threat Elevated - 20
Destroy 25 strike teams.

Repossession - 10
Seize 50 vehicles from enemy hands.

SME - 20
Gain the ability to drive and fly all vehicles.

Surface-To-Air - 10
Shoot down 50 helicopters while driving armor.

Evolutionary Step - 10
Use the Upgrade Menu to acquire an Upgrade.

Unnatural Selection - 40
Acquire all available upgrades.

The Cleaner - 20
Destroy 10 Military Bases or Infected Hives in New York City.

In The Web - 20
Consume 50 Web Targets.

Au - 40
Achieve a rating of Gold or better in all Events.

Nice Guy - 40
Complete the game while consuming 10 Civilians or fewer.

Hard To Kill - 60
Complete Story Mode in any difficulty without dying.

Speed Bumps - 20
Run over 500 characters in a single tank.

Pt - 60
Achieve a Platinum Medal in all Events.

Secret Achievements

Crossing The - 10
You've completed the Hunter Boss Encounter.

Errand Boy - 10
You've completed the Specialist Boss Fight.

Children Of Blacklight - 20
You've completed the Supreme Hunter Boss Battle.

On Instinct - 20
You've completed the Mother Boss Battle.

One Thousand Suns - 40
You've completed the Supreme Hybrid Boss Battle.

Hope - 20
You've discovered the truth behind Hope, Idaho.

Origin 20
You've discovered the history of Elizabeth Greene.
Source(s):
http://www.xbox360achievements.org/game/prototype/achievements/

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