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 M¢25  Funded By Mahalo ? |  October 19, 2009 11:57 AM

Explain Cell Mediated Immune System?

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October 19, 2009 01:37 PM
Cell-mediated immunity is an immune response that does not involve antibodies or complement but rather involves the activation of macrophages, natural killer cells (NK), antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen

Cellular immunity protects the body by:

1. activating antigen-specific cytotoxic T-lymphocytes that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;
2. activating macrophages and natural killer cells, enabling them to destroy intracellular pathogens; and
3. stimulating cells to secrete a variety of cytokines that influence the function of other cells involved in adaptive immune responses and innate immune responses.
Source(s):
http://en.wikipedia.org/wiki/Cell-mediated_immunity



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October 20, 2009 07:49 AM
Cell Mediated Immune System (CMIS). The immune system comprises T-lymphocytes which defend the body against pathogens, cancers and foreign structure like tissue transplants. Cells of Immune System. They are lymphocytes and antigen presenting cells like macrophages. A healthy human has about a trillion lymphocytes. Lymphocytes are of two types, T-lymphocytes (T-cells) and Blymphocytes (B-cells). Both of them develop in bone marrow (in foetus from yolk sac and then from liverspleen complex) from lymphatic stem cells by the process called haematopoiesis. Some of the young lymphocytes migrate into thymus for preprocessing. They are called T-lymphocytes. Afterwards they pass on to all the lymphoid tissues of the body and get lodged there. The other types of lymphocytes remain in the bone marrow and get preprocessed there. They are called B-lymphocytes. After being preprocessed Blymphocytes also migrate to all the lymphoid tissues of the body where they reside near but separate from T-lymphocytes.
Source(s):
http://www.examville.com


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October 22, 2009 05:41 PM
this immune system based an T-cells which are type of lymphocytes.it contain T-helper cells & T-cytotoxic cells.
T-helper cells interact with MHC II of antigen and become activated secreates cytokine which activate B-cells,Tc-cells phygocytic cells which by the process of phagocytosis kills the micrbes.

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