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 M¢25  Funded By Mahalo ? |  August 20, 2009 02:17 PM

What are the top ten most common diseases cause from DNA mutations?

List the name and description of the disease and how many people it affects
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August 20, 2009 04:20 PM
1. Sickle Cell Anemia is a blood disease that shortens life expectancy.Over 5 million in America have sickle cell.

2.Down Syndrome is a disease that affects the way a child develops mentally.For ever 1,000 babies one will be down syndrome.

3.Mental retardation is the lack of development of intellectual capacities.2.5 million mentally retarded people reside in the US

4.Alzheimer Disease causes dementia. 5% of the pe0ple in ages 65-74 have this disease

5. High Blood Pressure is when systolic blood pressure is over140. One in three US adults have high blood pressure

6. bubonic plague is an infection that travels through the skin and enters the lymphatics. The disease claimed over 200 million lives.

7.Heart Disease is conditions that affect the heart. 7 to 16% of the population have this disease.

8 Leukemia is the cancer of the blood and the bone marrow.Every year nearly 27,000 of the US population gets it.

9 Epidermolysis Bullosa is a a herited disease that affects mainly infants and children. Two out of 100,000 people get this disease.

10.Small pox is an infectios disease that is unique to humans. 1 in 26,000 have the small pox in US.
Asker's Rating:
• In each type of disease have scientist identified the gene that mutated?


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August 20, 2009 03:13 PM
Need to qualify the question a bit, because this (like pretty much everything interesting) is complex. Obviously, you are thinking about classic examples like "Tay-Sachs disease," but what about Downs Syndrome? Or what about sickle-cell disease, which can actually help with survival and so wasn't a "bad" mutation at all?

Here's a list I stole from a UK website. The numbers indicate frequency in births per thousand.

1.Familial combined hyperlipidemia – 5.0
2.Familial hypercholesterolemia – 2.0
3.Dominant otosclerosis – 1.0
4.Adult polycystic kidney disease – 0.8
5.Multiple exostoses – 0.5
6.Huntington’s disease – 0.5
7.Fragile X-syndrome – 0.5
8.Neurofibromatosis – 0.4
9.Cystic Fibrosis – 0.4
10.Duchenne muscular dystrophy – 0.3

The top two are high-cholesteral related: Would you consider these diseases?
Source(s):
http://www.blisstree.com/geneticsandhealth/ten-most-common-inherited-geneti...


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