Human DNA and chimpanzee DNA are very similar and according to according to a study done by the University of California, the "differences in how, when and where genes are turned on likely give rise to many of the physical differences" between humans and chimps. Physical differences between humans and chimpanzees include:

• Structure of the vocal tract.
• Upright posture.
• Anatomy of hands and feet.
• Female chimpanzees show sexual swellings during periods of estrus (humans under go the menstrual cycle instead).
• Hearing-- humans are attuned to two kHz up to four kHz, chimps are sensitive to one kHz or eight kHz.
• Humans have the widely exposed white sclera (white of the eye) surrounding the darker colored iris.
• Humans have an unusually large brain.
  
• Humans have less body hair.
• Humans have a flatter face.

This article has a more in depth analysis of the physical differences between humans and chimps: http://www.associatedcontent.com/article/13842/the_similarities_and_differences_between.html?cat=58 or you can check out the sources below.

YouTube: Jane Goodall: What separates us from the apes?
http://www.youtube.com/watch?v=51z7WRDjOjM
Source(s):
http://www.janegoodall.org/chimp_central/chimpanzees/similarities/default.a...
http://www.whyevolution.com/chimps.html
http://www.universityofcalifornia.edu/news/article/8411
http://www.associatedcontent.com/article/13842/the_similarities_and_differe...

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It depends on your viewpoint. Forgive me if this answers sounds smug, it is unintentional!

The difference in DNA is 1.1%.

Although nearly every chimp is bipedal, there is one chimp, called Oliver, that walked naturally on two legs. He is unable to do so now as he suffers from arthritis.

Another difference is chimps have far better memories than we do, at least short-term memories. They even leave college graduates in the shade with their capabilities. In memory tests they display what we would call a 'photographic memory'.

It used to be thought that chimps were imitators and that humans learned by independent thought. However, recent research shows that the opposite is true. Chimps are far more independent thinkers. Humans on the other hand, prefer to do what even one else is doing. Children learn best by imitating each other. Chimpanzees much prefer to do their own thing. The fact that we learn by imitating one another is now thought to be the reason for our success.

They are roughly five times stronger than we are.

I hope this answered, at least in part, your question.
Source(s):
http://yellowmagpie.com/chimpanzee-about

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