1 year, 9 months ago
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NDM-1 can hydrolyzes (destroy) or inactivates antibiotics in the beta-lactam family but what about fluoroquinolone group of antibiotics?
NDM-1 can hydrolyzes (destroy) or inactivates antibiotics in the beta-lactam family but what about amynoglycoside, macrolide, co-trimoxazole, tetracyclines, etc group of antibiotics?
The gene of NDM-1 produces “metallo-beta-lactamase”, an enzyme that hydrolyzes (destroy) and inactivates antibiotics in the beta-lactam family. Those antibiotics were, until recently, capable of killing most bacteria by inhibiting the synthesis of the bacterial cell wall layers.
The gene of NDM-1 produces “metallo-beta-lactamase”, an enzyme that hydrolyzes (destroy) and inactivates antibiotics in the beta-lactam family. Those antibiotics were, until recently, capable of killing most bacteria by inhibiting the synthesis of the bacterial cell wall layers.
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Fluoroquinolone group of antibiotics are completely different than the beta-lactam family. NDM-1 can hydrolyzes (destroy) or inactivates antibiotics in the beta-lactam family but not the Fluoroquinolone group of antibiotics. The antibiotics / chemotherapy in this group is ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin. These antibiotics are highly effective against NDM-1 and MRSA.
NDM-1 can hydrolyzes (destroy) or inactivates antibiotics in the beta-lactam family but not any amynoglycoside (gentamycin), macrolide (azithromycin), etc.
There is no specific reports on the mentioned antibiotics.
It is an open challenge.
The gene of NDM-1 produces “metallo-beta-lactamase”, an enzyme that hydrolyzes (destroy) and inactivates antibiotics in the beta-lactam family but not ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin.
NDM-1 can hydrolyzes (destroy) or inactivates antibiotics in the beta-lactam family but not any amynoglycoside (gentamycin), macrolide (azithromycin), etc.
There is no specific reports on the mentioned antibiotics.
It is an open challenge.
The gene of NDM-1 produces “metallo-beta-lactamase”, an enzyme that hydrolyzes (destroy) and inactivates antibiotics in the beta-lactam family but not ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin.
You can leave an optional "tip" with Mahalo's virtual currency, Mahalo Dollars. If you are asking a difficult question that might require some research, or if you'd like a wide variety of feedback, a higher tip often leads to more answers to your question.
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