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davepamn davepamn
 
M$1 June 13, 2009 09:38 PM

What is the micropump technology for delivering small molecule drugs?

Nanotechnology
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santhoshd santhoshd
 
 June 13, 2009 09:59 PM
Micropump is the brandname for Flamel Technologies' controlled-release product that enables extended, or both delayed and extended delivery, of small molecule drugs. Orally administered drugs generally absorbed in the small intestine are suitable for delivery via Micropump.

http://www.flamel.com/techAndProd/micropump.shtml

Micropump is one of several nanoparticle techniques available, together generally referred to as microspheres or nanospheres; one of these is technology from Aphios : http://www.aphios.com/company/Drug%20Delivery.htm

Recent developments in the area are often covered at http://www.nanotech-now.com/current-months-news.htm
Source(s):
http://www.flamel.com
http://www.aphios.com
http://www.nanotech-now.com

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davepamn davepamn
 
June 14, 2009 04:01 AM
1. Multiple-dose system containing 5,000 to 10,000 microparticles per capsule or tablet
2. 200-500 microns in diameter and released in the stomach and pass into the small intestine.
3. Each particle acts as a minature delilvery system and releases the drug by osmotic pressure at an adjustable rate over an extended period of time
4. Process avoids dosage dumping

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galaxybrow... galaxybrow...
 
June 13, 2009 10:15 PM
Micropump utilizes a variety of positive displacement pump technologies in its wide range of precision, low flow pumps, including external gear, gerotor, peristaltic, multiple and single piston, and sliding vane. Also available are high performance centrifugal pumps in a very compact size.

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badaspie badaspie
 
June 14, 2009 02:00 AM
There are several types of medical "micropump." One (called a micropump because it really is a tiny mechanical pump) uses shape-changing materials on a rigid substrate to create peristalsis-like movement, allowing the transport of tiny amounts of fluid without the use of conventional moving parts:

http://www.physorg.com/news82634710.html
http://www.medgadget.com/archives/2008/05/controllable_peristaltic_micropump.html
http://www.izm-m.fraunhofer.de/files/fraunhofer_engl/2006_micro_pumps_for_lab_technology_and_medicine.pdf

The Micropump by Flamel Technologies is a tablet containing microparticles, which release the drug through osmotic pressure as they pass through the gastrointestinal tract:

http://www.flamel.com/techAndProd/micropump.shtml

Aerogen's Micropump is a high-efficiency nebulization system to improve administration of inhaled drugs:

http://www.aerogen.com/products.html

In addition, there are various mechanical pumps of more or less conventional design which are referred to as micropumps because of their small size, some of which are used to deliver controlled doses of medication.

Tags: medicine, micropump

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