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M$1.00  Funded By Mahalo ? |  April 28, 2009 02:52 AM

Can anyone describe the 6 levels of the CDC pandemic chart. What occurs at each level?

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April 28, 2009 03:13 AM | view on twitter
RESPONSE ACTIVITIES BY PANDEMIC PHASE

Phase 1
Interpandemic Period:
No new virus in humans
No new virus subtypes havebeen detected in humans.
An virus subtype that has caused human infection may be present in animals.
If present in animals, the risk of humaninfection or disease is considered to be low.
Preparedness:
• Routine Monitoring

Phase 2
Interpandemic Period:
No new influenza virus subtypes have been detected in humans. However, a
circulating animal influenza virus subtype poses a substantial risk of human disease.
• Routine Monitoring

Phase 3
Pandemic Alert Period:
Human infection(s) with a new subtype, but no human-to-human spread, or at most rare instances of spread to a close contact.
• Same as above (review and update)
• Assess medical/vaccine/antiviral supplies
• Update vaccine program information
• Ensure legal/insurance issues resolved
• Review previous simulations and correct deficiencies
• Communication enhancement
• Assess surveillance, vaccine programs, antiviral availability, health services, emergency services, public health issues, communications
• Education

Phase 4
Pandemic Alert Period:
Small cluster(s) with limited human-to human transmission but spread is highly localized, suggesting that the virus is not well adapted to humans
• Same as above (review and update)
• Develop case definitions
• Review IC practice/procedures
• Assess “MASS VACCINATION” infrastructure
• Stratify risk group priority
• Ensure Health Services estimates current
• Ensure essential services
• travel advisories

Phase 5
Pandemic Alert Period:
Larger cluster(s) but human-to-human spread still localized, suggesting that the virus is becoming increasingly better adapted to humans, but may not yet be fully transmissible (substantial pandemic risk).
• Same as above (review and update)

Phase 6
Pandemic Period (not in North America):
Pandemic phase: increased and sustained transmission in general population. May have subsequent waves affecting different areas at different times.
• Same as above (review and update)
• Coordinate with bordering jurisdictions, provincial and federal authorities
• Vaccine purchase (when available)
• ADR activation (antivirals/vaccination)
• Ensure medical supplies
• Prioritize Lab resources
• Coordinate patient tracking
• Access human resources, volunteers
• Security (vaccine, drug, medical clinics, personnel)
• Activate emergency communications
• Review information tracking systems

Phase 6
Pandemic Period (in North America):
Increased and sustained transmission in general population. May have subsequent waves affecting different areas at different times with varying severity.
Full Activation
• State of emergency declared?
• Resource reallocation
• may have decrease in incidence locally but high
risk of 2nd wave due to ongoing pandemic
elsewhere

Post pandemic Period:
Return to Interpandemic Period.
• Return to Phase 1
• Maintain heightened awareness/surveillance
• Review Pandemic / Lessons learned
• Review economic impact to DRHD
• Return to routine monitoring
The distinction between phase 1 and phase 2 is based on the risk of human infection or disease resulting from circulating strains in animals. The distinction would be based on various factors and their relative importance according to current scientific knowledge. Factors may include: pathogenicity in animals and humans; occurrence in domesticated animals and livestock or only in wildlife; whether the virus is enzootic or epizootic, geographically localized or widespread; other information from the viral genome; and/or other scientific information

The distinction between phase 3, phase 4 and phase 5 is based on an assessment of the risk of a pandemic. Various factors and their relative importance according to current scientific knowledge may be considered. Factors may include: rate of transmission; geographical location and spread; severity of illness; presence of genes from human strains (if derived from an animal strain); other information from the viral genome; and/or other scientific information.
Source(s):
http://www.region.durham.on.ca/departments/health/disease_prevention/annexC...



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April 28, 2009 03:52 AM | view on twitter
According to World Health Organization:

"In nature, influenza viruses circulate continuously among animals, especially birds. Even though such viruses might theoretically develop into pandemic viruses, in Phase 1 no viruses circulating among animals have been reported to cause infections in humans.

In Phase 2 an animal influenza virus circulating among domesticated or wild animals is known to have caused infection in humans, and is therefore considered a potential pandemic threat.

In Phase 3, an animal or human-animal influenza reassortant virus has caused sporadic cases or small clusters of disease in people, but has not resulted in human-to-human transmission sufficient to sustain community-level outbreaks. Limited human-to-human transmission may occur under some circumstances, for example, when there is close contact between an infected person and an unprotected caregiver. However, limited transmission under such restricted circumstances does not indicate that the virus has gained the level of transmissibility among humans necessary to cause a pandemic.

Phase 4 is characterized by verified human-to-human transmission of an animal or human-animal influenza reassortant virus able to cause “community-level outbreaks.” The ability to cause sustained disease outbreaks in a community marks a significant upwards shift in the risk for a pandemic. Any country that suspects or has verified such an event should urgently consult with WHO so that the situation can be jointly assessed and a decision made by the affected country if implementation of a rapid pandemic containment operation is warranted. Phase 4 indicates a significant increase in risk of a pandemic but does not necessarily mean that a pandemic is a forgone conclusion.

Phase 5 is characterized by human-to-human spread of the virus into at least two countries in one WHO region. While most countries will not be affected at this stage, the declaration of Phase 5 is a strong signal that a pandemic is imminent and that the time to finalize the organization, communication, and implementation of the planned mitigation measures is short.

Phase 6, the pandemic phase, is characterized by community level outbreaks in at least one other country in a different WHO region in addition to the criteria defined in Phase 5. Designation of this phase will indicate that a global pandemic is under way.

During the post-peak period, pandemic disease levels in most countries with adequate surveillance will have dropped below peak observed levels. The post-peak period signifies that pandemic activity appears to be decreasing; however, it is uncertain if additional waves will occur and countries will need to be prepared for a second wave.

Previous pandemics have been characterized by waves of activity spread over months. Once the level of disease activity drops, a critical communications task will be to balance this information with the possibility of another wave. Pandemic waves can be separated by months and an immediate “at-ease” signal may be premature.

In the post-pandemic period, influenza disease activity will have returned to levels normally seen for seasonal influenza. It is expected that the pandemic virus will behave as a seasonal influenza A virus. At this stage, it is important to maintain surveillance and update pandemic preparedness and response plans accordingly. An intensive phase of recovery and evaluation may be required. "

Source(s):
http://www.who.int/csr/disease/avian_influenza/phase/en/index.html


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