Judging by several articles, AIN usually includes the tubular renal area. eMedicine's overview article defines interstitial nephritis as "Kidney diseases that involve structures in the kidney outside the glomerulus are broadly referred to as tubulointerstitial." This article (http://emedicine.medscape.com/article/243597-overview) includes discussion of differential and treatment.

A Nephrology Channel article states: "Most AIN is caused by an acute allergic reaction to a medication, including antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs)..." and lists common drugs. This article can be found at http://www.nephrologychannel.com/ain/index.shtml

As far as Acute Tubular Nephritis, MyClinicalNotes says "ATN is characterised morphologically by destruction of tubular epithelial cells and clinically by acute loss of renal function" but I can find no source citation. myclinicalnotes.com/kidney/acute-tubular-nephritis. Another definition (without a specific source) states AIN is a kidney disease characterized by acute onset, a decreased renal function and microscopic changes mainly located to the renal interstitium (edema and/or infiltration of white blood cells). (http://www.ravnskov.nu/terminology.htm)

Follow this up with a check of a medical encyclopedia at your local library.
Source(s):
http://emedicine.medscape.com/article/243597-overview
http://www.nephrologychannel.com/ain/index.shtml
http://myclinicalnotes.com/kidney/acute-tubular-nephritis
http://www.ravnskov.nu/terminology.htm


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