Angiotensin II Receptor Blocker is a prescription drug that helps to lower blood pressure in people with hypertension. Angiotensin II is a hormone that causes vasoconstriction thus blocking it from binding inhibits vasoconstriction. The blood vessels are more open as a result and the heart doesn't have to work as hard and blood pressure is lower.
Fast Facts:
- Half-life range: 6-24 hours
- Side effects: Stomach problems, back and leg pain, dizziness, insomnia, upper respiratory infectionMayo Clinic: Angiotensin II receptor blockers
- Prescribed: If ACE inhibitors are not well tolerated
- Uses: May delay diabetic nephropathy in type II diabetes patients
- Advantages: Does not break down kinins to cause cough or angioedema like ACE inhibitors
- Invented: 1986
- First produced: Losartan
- Not for use by pregnant womenMayo Clinic: Angiotensin II receptor blockers
Alzheimer's Disease
In 2008, a comparative study using a large database of medical records revealed that patients taking angiotensin II receptor blockers are 35-40 percent less likely to develop Alzheimer's, and that patients already developing Alzheimer's were up to 45 percent less likely to develop delirium, be admitted to nursing homes or die.Physorg.com: Angiotensin receptor blockers are lower incidence, progression of Alzheimer's disease It is believed that their effectiveness may stem from their promotion of nerve recovery.Physorg.com: Angiotensin receptor blockers are lower incidence, progression of Alzheimer's disease It's possible that these effects will lead to their widespread use to prevent Alzheimer's. Disclaimer: The content in this page is not a substitute for professional medical advice. Please contact your doctor before taking any Angiotensin II Receptor Blocker.
ARB Competitors
Prescription
Alpha Blocker
Vasodilator
Aldosterone Antagonist
Adrenergic Receptor Agonist
Adrenergic Neuron Blocker
Central Alpha Agonist
ARB Holistic Alternatives
Alive: Take the Pressure off Hypertension With Homeopathy (February 2006)
Prevention: Lower Your Blood Pressure Naturally (February 24, 2005)
WebMD: Tea Drinkers Reap Blood Pressure Benefits (July 26, 2004)
JAMA: Chocolate and Blood Pressure in Elderly Individuals With Isolated Systolic... (August 27, 2003)
WebMD: Lower Blood Pressure Naturally (2003)
National Heart, Lung, and Blood Institute: Lowerig Your Blood Pressure With DASH
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