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Amitriptyline is a tricyclic antidepressant. Amitriptyline is a white, odorless substance (which happens to taste like licorice), usually dispensed in oral form. Amitryptyline inhibits reuptake of serotonin and noradrenaline. Amitryptyline's side effect profile has made it less commonly prescribed, especially since new tricyclic drugs, heterocyclic antidepressants, and SSRIs have become very widely used. However, it is still considered a "baseline" antidepressant, a standard to measure other antidepressants by.
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Fast Facts:
- Sold under the names Elavil, Tryptanol, Endep, and others
- Approved usage for depression and bedwetting
- Unapproved for headaches, insomnia, chronic pain, Irritable Bowel Syndrome (IBS), and a number of other conditions
- Common side effects: muscle stiffness, extreme weight gain, drowsiness, dizziness, nauseaMedLinePlus: Side Effects
- Rare side effects: tinnitus, hypotension, mania, psychosis, arrhythmias, depressionMedLinePlus: Side Effects
- May take 2 to 3 weeks to feel the full benefit
Comparisons
Amitriptyline has been used in the past as a first-line antidepressant, but more recently has been recommended for inpatient use, where SSRIs are recommended for outpatient treatment, due to their less signficant side effect profile.MDConsult: Amitriptyline for inpatients and SSRIs for outpatients with depression? Systematic review and meta-regression analysis. However, despite the incidence of side effects that amitriptyline brings, it is still considered the 'reference antidepressant' by many providers.NLM Gateway: Is amitriptyline the reference antidepressant? Disclaimer: The content in this page is not a substitute for professional medical advice. Please contact your doctor before taking Amitriptyline.
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Amitriptyline on Amazon
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On-line field-amplified sample stacking in capillary electrophoresis for analysis of amitriptyline and its metabolite nortriptyline in plasma [An article from: Analytica Chimica Acta] - $8.95
This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com M...Amazon
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Olympian Labs Chondroytamine Hcl - $15.29
Chondroytamine HCL is a powerful combination of Chondroitin Sulfate and Glucosamine HCL that may help alleviate, and possibly repair, the damage done to the joints and bones by ost...Amazon
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Amitriptyline 50mg Tablets
FDA-Approved Generic Amitriptyline 50mg. PRESCRIPTION REQUIRED. See Instructions Below..Amazon
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Amitriptyline Holistic Alternatives
- MayoClinic.com: Depression: Complementary and Alternative Medicine
- National Center for Complementary and Alternative Medicine (NCCAM): St. John's Wort
- Healing with Nutrition: Beating the Blues with Natural Antidepressants
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