Alpha 1 Antitrypsin Deficiency

Alpha 1 antitrypsin deficiency is a lack of the protein alpha 1 antitrypsin protein that is produced in the liver. A deficiency of alpha 1 antitrypsin can lead to lung disease and liver disease. Alpha 1 antitrypsin deficiency is an inherited genetic condition.American Liver Foundation: Alpha-1 Antitrypsin Deficiency There is no cure for alpha 1 antitrypsin deficiency and the condition can be fatal. In December 2008, it was reported that pop-star Michael Jackson is very ill due to suffering from an alpha 1 antitrypsin deficiency.American Lung Association site: [http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=2058817&content_id=%7B54DBE29B-FD26-4854-B918-AA66BA87503F%7D¬oc=1 Alpha-1 Antitrypsin Deficiency EmphysemaNewsday.com: Biographer: Michael Jackson Needs Lung Transplant (December 22, 2008)

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The content in this page is not a substitute for professional medical advice. If you think you have Alpha 1 Antitrypsin Deficiency, please consult your doctor.

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Fast Facts

Fact:

Alpha 1 antitrypsin is a protein produced in the liverAmerican Liver Foundation: [http://www.liverfoundation.org/education/info/alphaone/ Alpha-1 Antitrypsin Deficiency
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Alpha 1 antitrypsin plays a role in breaking down enzymes in several organs including the lungsAmerican Liver Foundation: [http://www.liverfoundation.org/education/info/alphaone/ Alpha-1 Antitrypsin Deficiency
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Alpha 1 antitrypsin destroys neutrophil elastase, an enzyme that normally digests aging cells and bacteria in the longsAmerican Lung Association site: Alpha-1 Antitrypsin Deficiency Emphysema
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Alpha 1 antitrypsin is supposed to stop the neutrophil elastase before it can damage the lung tissueAmerican Lung Association site: Alpha-1 Antitrypsin Deficiency Emphysema
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The deficiency of alpha 1 antitrypsin leads to the damage of lung tissueAmerican Lung Association site: Alpha-1 Antitrypsin Deficiency Emphysema
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Can potentially become chronic and fatalAmerican Lung Association site: Alpha-1 Antitrypsin Deficiency Emphysema
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Is an inherited disorderAmerican Liver Foundation: [http://www.liverfoundation.org/education/info/alphaone/ Alpha-1 Antitrypsin Deficiency
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Approximately 1 in 2,500 people have alpha 1 antitrypsin deficiencyAmerican Liver Foundation: [http://www.liverfoundation.org/education/info/alphaone/ Alpha-1 Antitrypsin Deficiency
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Found in all ethnic groups but most frequently occurs in white people of European ancestryAmerican Liver Foundation: [http://www.liverfoundation.org/education/info/alphaone/ Alpha-1 Antitrypsin Deficiency

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