Alli

Categories: Health | Drugs
    • Medical name: Orlistat
    • Prescription name: Xenical
    • Manufacturer: GlaxoSmithKline
    • Use: Weight loss
    • Available over-the-counter
    • Route: Oral
    • Cost: About $2 per day
    • Disclaimer: The content in this page is not a substitute for professional medical advice. Please contact your doctor before taking Alli.
  • The over-the-counter version of Xenical, Alli is a weight loss drug that works by blocking fat absorption. Alli's dosage is 60 mg, half the dosage of Xenical. Originally only available with a prescription, orlistat, the medical name for Alli, was approved by the Food and Drug Administration in the United States in 1999.FDA News: FDA Approves Orlistat for Over-the-Counter Use (February 7, 2007)
  • Mode of Action

    Alli works by blocking the absorption of the 25% of fat a person consumes in the case of the over-the-counter dosage, and 30% in the case of the prescription dosage.#Pittsburgh Post-Gazette: Diet drug debuting with big splash(June 8, 2007), WebMD: Prescription Weight Loss Medications
  • Side Effects

  • Obesity Drugs

    The field of obesity drugs is long and fraught with failure. Historical Roman treatments included laxatives and purgatives. In 1933, DNP was introduced, and discovered to cause fatal increases in heat at a cellular level.MedCEU: Obesity: The Disease, Treatment, and Drugs Amphetamines became popular around the same time, combined with a number of other drugs to counteract the side effects of amphetamines, but were implicated in a number of deaths in the late 60's and were banned for weight loss in 1979. A combination of phentermine and fenfluramine became extremely popular in 1992, and subsequently was found to cause heart disease in up to 30% of users.MedCEU: Obesity: The Disease, Treatment, and Drugs

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