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- Full name: Angiotensin-converting enzyme inhibitor
- Typically taken orallyMedicineNet: Examples of ACE Inhibitors
- Can cause birth defectsNew England Journal of Medicine: Major congenital malformations after first-trimester exposure to ACE inhibitors
- Provoke the body to reduce blood pressureMedicineNet: How ACE Inhibitors work
- Can interact with NSAIDS, antacids, lithium, etc.WebMD: ACE Inhibitors for high blood pressure
- Can cause a rare but fatal condition, angioedemaMayo Clinic: Angiotensin-converting enzyme (ACE) inhibitors
- Can also cause reduced white cell counts or allergic reactionsMedicineNet: How ACE Inhibitors work
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An ACE inhibitor is a class of drugs that inhibit angiotensin-converting enzyme, which is used by the body to trigger the enlargement of blood vessels. Doctors often prescribe a drug of this class as first-line treatment for hypertension and heart failure, as well as a number of other conditions, such as strokes and kidney dysfunction resulting from diabetes.Geriatric Times: Understanding the Biology of ACE Inhibitors WebMD: ACE Inhibitors for high blood pressure
Often another drug, such as an angiotensin II receptor blocker or a diuretic, must be taken in combination with an ACE inhibitor to achieve blood pressure goals. In fact, a number of combined drugs (i.e., an ACE inhibitor along with one or more additional drugs in a single pill) are suggested in some modern research, such as beta-blockers or statins.Ingenta Connect: Challenges for the Prevention of Primary and Secondary Stroke
Examples
- Benazepril
- Enalapril
- Lisinopril
- Ramipril
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ACE Inhibitor Questions
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Direct Renin Inhibitor
Positive Inotrope
ACE Inhibitor Drugs
- Lisinopril
- Vasotec
- Altace (Ramipril)
- Accupril (Quinapril)
- Lotensin (Benazepril)
- Monopril (Fosinopril)
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