The 2010 Sun Belt Conference football schedule began with the September 2, 2010 game between Middle Tennessee State University and the University of Minnesota. The Blue Raiders lost to Minnesota by a score of 24 to 17 at their home stadium in Murfreesboro, Tennessee.http://espn.go.com/ncf/recap?gameId=302452393 A second opening day game was also played in the Sun Belt Conference between Florida Atlantic University and the University of Alabama-Birmingham. FAU won the close game by a score of 32 to 31 at UAB's home field in Birmingham, Alabama.http://espn.go.com/ncf/recap?gameId=302450005

Throughout the 2010 regular season schedule, there are several games that are slated for national television coverage including the September 18 game between North Texas University and Army which will air on CBS College Sports Network, the October 5 game between Troy University and Middle Tennessee which will air on ESPN2 and the October 8 matchup between the University of Louisiana-Lafayette and Oklahoma State University which is also scheduled for broadcast on ESPN2.http://www.sunbeltsports.org/SportSelect.dbml?DB_LANG=C&DB_OEM_ID=4100&SPID=1808&SPSID=22165

The last day of the 2010 regular season will be December 4, 2010. There will be two games involving Sun Belt Conference teams on that day, beginning with a game between Florida Atlantic and Troy and ending with a game between Florida International and Middle Tennessee.http://www.sunbeltsports.org/SportSelect.dbml?DB_LANG=C&DB_OEM_ID=4100&SPID=1808&SPSID=22165