Week two of the 2010 NFL season includes 15 games on Sunday, September 19, 2010, plus the Monday Night Football matchup on September 20, 2010. Each of the 32 National Football League teams play in week two, with both divisional and non-divisional match-ups filling the schedule.http://www.nfl.com/schedules/interactive#/week=2

Early Sunday games include the Pittsburgh Steelers at Tennessee Titans, Philadelphia Eagles at Detroit Lions, Baltimore Ravens at Cincinnati Bengals, Arizona Cardinals at Atlanta Falcons, Miami Dolphins at Minnesota Vikings, Kansas City Chiefs at Cleveland Browns, Buffalo Bills at Green Bay Packers and Chicago Bears at Dallas Cowboys. Week two action continues Sunday afternoon as the Seattle Seahawks visit the Denver Broncos, Jacksonville Jaguars visit the San Diego Chargers, Houston Texans visit the Washington Redskins and the New England Patriots visit the New York Jets. On Sunday night, the New York Giants travel to play the Indianapolis Colts and on Monday Night Football, the New Orleans Saints play at the San Francisco 49ers.http://www.nfl.com/schedules/interactive#/week=2

Fresh off the opening week of play in the 2010 NFL season, teams return to the field to continue their campaigns during week two. A number of games are notable during the week including the AFC East battle between the New England Patriots and New York Jets and the AFC North game between the Baltimore Ravens and the Cincinnati Bengals. Sunday night features the Manning brothers head to head as Peyton and Eli Manning face off with the Indianapolis Colts taking on the New York Giants. Monday Night Football includes the defending Super Bowl-champion New Orleans Saints visiting the San Francisco 49ers.

Sunday afternoon 1:00 p.m. EST games include an AFC North match-up between Ray Lewis and the Baltimore Ravens as they visit Chad Ochocinco and Terrell Owens of the so-far-winless Cincinnati Bengals.http://www.nfl.com/schedules/interactive#/week=2

Divisional battles continue in the late afternoon games as a heated AFC East rivalry is featured front and center at the brand new Meadowlands stadium. Tom Brady and the New England Patriots hope to silence the New York Jets and head coach Rex Ryan following an off-season filled with trash talk.http://www.bostonherald.com/blogs/sports/rap_sheet/index.php/2010/08/23/jets-coach-rex-ryan-responds-to-patriots-qb-tom-brady-and-doesnt-seem-to-mind/

The Sunday night game features a battle of the Manning brothers when Peyton Manning and the Indianapolis Colts play Eli Manning and the New York Giants for only the second time in NFL history.http://www.nfl.com/schedules/interactive#/week=2

The defending Super Bowl champion New Orleans Saints make their first Monday Night Football appearance to close out the 2010 week two schedule when they head to the West Coast to battle the rebuilding San Francisco 49ers.http://www.nfl.com/schedules/interactive#/week=2